BCH447H1 Study Guide - Phylogenetic Tree, Neutral Mutation, Genetic Drift

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22 Apr 2014
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Conceptually, we look at the differences in the amino acid sequences of the same protein in different species and compare the difference. Using the difference factor we can create a phylogenetic tree. This is shown in the notes for lecture one. We look at the difference between species and create a phylogenetic tree based on their distance from each other with the distance being based on genetic difference number once more are seen. Note that it is okay to wing it a little as long as the numbers are relatively the same. In our tree we see that caw is more distant from humans than monkeys are. We also see that the chicken is more related to the cow than to the humans. Once more, the tuna should be equidistant also. The sequence here was determined through protein sequencing a technique pioneered by sanger.