MIP 300 Lecture Notes - Bactericide, Ethylene Oxide, Therapeutic Index
26 Jun 2014
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Sterilization no living cells, spores, or viruses. Disinfectant/disinfection killing, inhibiting, removing organisms that cause disease, from inanimate objects. Sanitization reducing microbial #s to levels safe for the public. Antiseptics kill or inhibit infection causing organisms from living tissue. Germicides kill certain organisms, i. e. fungicide, viricide, bactericide. Concentration of anti-microbial agent higher works faster. Local environment chemicals in the environment may increase or decrease anti- microbial efficiency. Organic matter may reduce efficiency of anti-microbial agents. Sterilize heat sensitive objects, i. e. syringes, petri dishes etc. Filtration backpacking filters surgical masks, cotton plugs, air filters, liquid filters. 0. 2 m pore membranes do not allow bacteria, protozoa, fungi through. Used mostly in research labs inhibited by glass, paper, h2o, and dirt. Stop nucleic acid synthesis small therapeutic ratio. Antibiotics are thought to have evolved 900 million years ago, long before. When soil bacteria are analyzed they are resistant to an average of 7 8 animals antibiotics.
