BIO 3153 Study Guide - Final Guide: Tubulin, Microfilament, Keratin
17 Jul 2014
School
Department
Course
Professor
Document Summary
Soluble subunit: smallest element of structure that will not breakdown any further (monomer or single actin protein) Subunits form filaments: causes changes in cell shape. Disassembly of filaments and rapid diffusion of subunits (moves to a different part. Nucleation: molecule starts off the formation of multiple subunits to get filament started. Signal = salt (induces nucleation, increase in salinity increases activity of. 4. phase: y axis = total subunits, 0-100 total amount of subunits in cytoplasm to, x axis = time after salt addition (before salt = 0) Equilibrium phase: formed microfilament, losing and gaining subunits (dynamic. Protofilaments: 13 protofilaments form microtubule (rings, not sheets, multiple protofilaments increase thermal stability, weak non covalent bonds, weaker than covalent bonds, strong enough to keep together but weak enough to be broken without breaking bonds (dynamic) Actin: soluble subunit, twisted formation, single protein, monomer, requires energy, hydrolyses atp, 1 open/exposed binding site in the middle (closer to minus end/alpha/bottom) (not like tubulin)
