PSL300H1 Lecture Notes - Lambda Phage
Document Summary
+ /k + pump (2/3 of energy for neurons for the pumps) Na+/k+ inequality potential difference of -10 mv small potential difference o o. Resting membrane is most permeable to k+ ion. K+ diffuses out of cell, down concentration gradient, via 2-pore family of k+ channels. K+ accumulate outside membrane, leaving a net negativity inside membrane. Membrane potential at equilibrium is determined by the concentration gradient o can be calculated using nernst equation. + equilibrium potential if the membrane properties change to make the membrane most permeable to na+, then there is a net na+ current inward. September 12, 2007 at equilibrium, there is a net cation accumulation inside the membrane. Membrane potential is positive inside with respect to the outside ena+ = +50 mv. Na+/k+ pump is always working the concentration gradient is the driving force for the diffusion of the ions.
