HLTB21H3 Chapter : HLTA01 Ch 8

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3 Jan 2012
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Dr. pettenkofer: plague miasmas ; bad vapours f/ marshes that contaminated water and transmitted through air. > caused by laziness & lack of hygiene. Louis pasteur speculated spoilage & fermentation to be the cause (1857) > a contagionist who believed in the germ theory (1862) 1500, girolamo fracastoro"s theory of seed contagion. Theory of spontaneous generation (until the 1850s) > francesco redi refuted the theory that flies had to land on the lifeless matter, deposit their eggs & then give birth to maggots (1668) > lazzaro spallanzani refuted the theory b/c microbes arise f/ other microbes (1767) Koch"s postulates for distinguishing the causative agent for a microbial disease. Symptoms: dehydration, ruptured capillaries, discoloured skin (black & blue), diarrhea rice water stools , headache, vomiting, convulsions, muscle cramps, abdominal pain, electrolytes & water loss, death. Ad 900, rhazes concluded the disease incurable. Thomas sydenham (1624-89) used the term cholera morbus = state of anger.