PSL300H1 Study Guide - Aldosterone, Glycogen, Osteoblast
Document Summary
May act on multiple tissues alter activity of target cell, action must be terminated, feedback mechanism needed. Stimulus hormone receptor intracellular signalling pathways cell activity . Classic hormone: conducted through the bloodstream to the rest of the body. Neuro-hormone: neuron release hormone at synapse through exocytosis into the bloodstream: short distance. Autocrine: hormone act on the same cell of secretion. Paracrine: hormone secreted by one cell and diffused to adjacent cells (can be both: short and long distance. Neuro-transmitters: synaptic release of hormone from inter-synaptic cleft to target cell, distance traveled depends on the length of the axon. Ligand + receptor = ligand receptor complex triggers cellular response. Oxytocin and control of uterine contractions amplify cervical stretch until baby is born. Lecture 2 classification of hormone and control of release. 1. peptide/ protein: 3 or more amino acids: most made in advance, stored in vesicles, synthesized like secreted proteins.
