ANP 1105 Lecture : muscles and metabolism.doc

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1105
• Professor: Jacqueline Carnegie

Document Summary

As muscles contract, atp supplies the energy fro cross bridge movement and detachment and for operation of the calcium pump in the sarcoplasmic reticulum. Muscles store only 4 to 6 seconds" worth of atp reserves (usually just enough energy to begin movement) Since atp is the only energy source used directly for contractile activities, it must be regenerated as fast as it is broken down in order for contraction to continue. After atp is hydrolyzed to adp and inorganic phosphate in muscle fibres, it is regenerated quickly by 1 or more of these pathways: direct phosphorylation of adp to creatine phosphate. During vigorous activity, the demand for atp soars and the atp stored in working muscles is consumed within a few twitches. Creatine phosphate (cp), a unique high-energy molecule stored in muscles, is used to regenerate atp while the metabolic pathways are adjusting to the suddenly higher demands for atp.