BIO120H1 Lecture 15: lecture 15.docx

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18 Apr 2012
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BIO120H1 Full Course Notes
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BIO120H1 Full Course Notes
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3 definitions broadest level: functional unit of inheritance semi broad: unit of hereditary infordation in chromosome consisting of dna. Narrow: dna sequence composed of codons, a sequence of 3 nucleotides. 3 scenarios. carrying mutation isn"t good, pollinators recognize it as different and they don"t come to the different flower. Maybe another pollinator comes around and prefers this flower. If so, then its fitness enhancing and flower survives and populates year after year. Stable change in dna sequence which causes change in genotype. Effects: deleterious (fitness is just lowered), neutral or lethal. No fixed mutation rate, environment can change it (nuclear industry) Types: a) point mutation {most important} b) insertion/deletion {jumping gene} c) changes in repeat number d) deleterious- complete chromosomal rearrangement. Motoo kimura: first person to recognize that mutations could be neutral. The reason they aren"t killing us because they recessive. 3-1 ratio in f2 generation most organisms carry 2 copy"s of each gene.

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