HLTB21H3 Chapter Notes - Chapter 13: Tuberculin, Macrophage, Victorian Era
Document Summary
Called consumption 1850s to 1900s: those inflicted were said to have artistic talent and powers of sexual seduction. Pulmonary tb = tuberculosis of the lungs: m. tuberculosis. Can affect other organs: sometimes swelling of lymph nodes (scrofula) 1000 to 400 bc, fusion of vertebrae/deformation of spine (pott"s disease) 100 bc. M. bovis: affect adrenal cortex destroys adrenal function (addison"s disease) M. bovis infrequent in humans requires low o2 levels to grow. M. tuberculosis specific to human requires high o2 levels to grow: spread via droplets of saliva and mucus. M. tuberculosis believed to evolve from m. bovis after cattle were domesticated. Egypt middle east, greece, india via nomadic indo-europeans. Hippocrates: due to bad air, but not considered contagious. Aristotle: due to bad and heavy breath , might be contagious. Galen: was contagious, but contagious agent couldn"t be found. During middle ages, royalty cured scofulas by touching it. In victorian age, tb was attractive due to lack of lesions.
