HSCI 100 Lecture Notes - Bone Marrow, Lymphatic Vessel, Severe Combined Immunodeficiency

• School: Simon Fraser University
• Department: Health Sciences
• Course: HSCI 100
• Professor: Nienke Van Houten

Document Summary

55% plasma: albumin majority of plasma transport and osmotic pressure, globulin fat and vitamin transport and antibiotic, fibrinogen for blood clots. 45% red blood cells & platelets: no nucleus and organelles, 120 day life span, hemoglobin bound (280 mill!) Red blood cell production: bone marrow produces, erythropoietin (epo) excreted from kidneys stimulate red marrow when low o2, stop production of epo, disfunctions include, anemia (less rbcs or hemoglobin, sickle-cell anemia, Genetic rbc hemoglobin shape dysfunction. (low 02: hemolytic disease of newborns . White blood cells: red bone marrow too controlled by colony stimulating factor, has nucleus, granular. Neutrophil no stain: agranular no granules. Parasitic worm infections and allergic: basophil. Release histamine for allergic reaction: neutrophil. Develops into b and t cells: monocytes, phagocytosis to engulf pathogens. White blood cell deficiencies: severe combined immunodeficiency disease (scid) White blood cells lack the enzyme to fight infections: leukemia. Cancer which causes uncontrollable proliferation: infectious mononucleosis.