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suvs.kabiLv1
28 Sep 2021
Suppose you have two A-B-type exotoxins, A-B and A’-B’. A-B binds specifically to all
MHC-II cells and blocks vesicle trafficking. A’-B’ binds specifically to all MHC-I cells and
stops protein synthesis.
a. What would a hybrid toxin, A’-B, do to fibroblast (skin) cells? Provide your rationale.
b. What would a hybrid toxin, A-B’, do to fibroblasts? Provide your rationale.
c. What would a hybrid toxin, A’-B, do to macrophages? Provide your rationale.
d. What would a hybrid toxin, A-B’, do to macrophages? Provide your rationale
Suppose you have two A-B-type exotoxins, A-B and A’-B’. A-B binds specifically to all
MHC-II cells and blocks vesicle trafficking. A’-B’ binds specifically to all MHC-I cells and
stops protein synthesis.
a. What would a hybrid toxin, A’-B, do to fibroblast (skin) cells? Provide your rationale.
b. What would a hybrid toxin, A-B’, do to fibroblasts? Provide your rationale.
c. What would a hybrid toxin, A’-B, do to macrophages? Provide your rationale.
d. What would a hybrid toxin, A-B’, do to macrophages? Provide your rationale
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