GMED2001 Study Guide - Final Guide: Portal Vein, Portal Venous System, Alcoholic Liver Disease

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Alcohol cirrhosis: is caused by the toxic effects of alcohol on the liver, it progresses with fatty infiltration, fibrosis and cirrhosis. Fat deposition (deposition of triglycerides) occurs within the liver al lipids mobilised from adipose tissue or dietary fat intake may contribute to fat accumulation. Cessation of alcohol intake reverses the fatty accumulation, but fibrosis and liver damage are irreversible. Alcoholic liver disease: progresses from fatty liver (steatosis) to alcoholic cirrhosis. Ascites: is the accumulation of fluid in the peritoneal cavity and is the most common complication of cirrhosis. Cholecystitis: can be acute or chronic, but both forms are almost always caused by a gallstone lodged in the cystic duct. The gallbladder becomes distended and inflamed, with pain similar to that caused by gallstones. Pressure against the distended wall of the gallbladder decreases blood flow and may result in ischaemia, necrosis and perforation. Gallstones: there are 2 types of gallstones - cholesterol and pigmented.

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