IMED3001 Final: IMED3001_ Heart failure (HFpEF)
9 Jan 2021
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Document Summary
Imed3001: heart failure (hfpef) with preserved left ventricular systolic function. The clinical term heart failure with preserved ejection fraction (hfpef) is used to include a range of different conditions and previous terminology including diastolic" heart failure or hypertensive" heart disease. The hypertrophic" and restrictive" cardiomyopathies are usually considered under hfpef as the ef is often normal or only mildly reduced (ef>45-50%). Contraction (systolic function) is near normal (ef > 45 - 50%) The left ventricular myocardium becomes thickened/ hypertrophied. (e. g. hypertrophic cardiomyopathy) with increased apoptosis of myocardial cells and increased fibrosis throughout the myocardium. With the familial/ genetic/ idiopathic forms there is usually muscle fibre disarray. Foreign" substances are interspersed between the myocardial cells or deposited in the myocardium. Approximately half (estimates between 40 to 71%) Prevalence 1. 1 to 5. 5% of the population. Measurement of circulating b-type natriuretic peptide (bnp) Assess lv ef, for lvh, diastolic dysfunction. Measure lv end diastolic pressure, pa capillary wedge pressure.
