PHYS1008 Study Guide - Final Guide: Gamma Camera, Partial Seizure, Biodistribution
2 Aug 2018
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Document Summary
High resolution tomographic images of the bio-distribution of a radiopharmaceutical or radio-tracer in the body. Carriers attached to radio-isotopes, carrier depends on what is being looked at. Two key differences between pet and spect: type of radionuclide used, image acquisition equipment. Positron emitter/radioisotope/radiotracer introduced to body on a biologically active molecule. The radioisotope travels to tissue of interest and undergoes positron emission decay (beta decay) Positron annihilates with a nearby electron in an annihilation reaction, destroying both. Two gamma photons are emitted in opposite directions. Pet scanner detects these emissions coincident in time. Large number of low-atomic number elements for which positron emitters exist. Hence, positron emitters can be incorporated into many biologically active compounds including isotopic forms of oxygen, carbon, nitrogen and fluorine. The radioisotope is the part of the radiotracer which emits the positrons. Radioisotopes need to be produced by a cyclotron.
