BIOL 3P50- Final Exam Guide - Comprehensive Notes for the exam ( 35 pages long!)

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Dna type: however, rna typically found in cells as single-stranded molecule. Central dogma: transcription: rna synthesis directed by dna template, translation: synthesis of proteins directed by rna template, unidirectional rna sequences are never determined by protein templates nor is dna made on. Genomics: advent of rapid, automated dna sequencing methods has led to determination of complete genome sequences. Identification of sequences that direct gene expression, dna replication, chromosome segregation, and recombination can all be facilitated by comparing genome sequences. High-energy bonds: formation of covalent bonds involves an increase in free energy, monomeric precursors are converted to high-energy activated precursors using energy of atp, which spontaneously unite to form larger molecules. In right handed dna, glycosidic bonds are in anti conformation. Individual folded chains associate with each other: way in which subunits associate does not change how individual polypeptides fold, components of a protein oligomer depend on association with each other.

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