BIOL 202 Study Guide - Serial Killer, Nondisjunction, Variable Number Tandem Repeat

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If a female undergoes a non-disjunction event on chromosome 21 prior to the onset of meiosis ii, what proportion of the products of this meiosis will result in: down"s syndrome, unaffected offspring, miscarriage. If a female undergoes a non- disjunction event involving chromosome 21 during meiosis. A young man comes to you claiming that his mother was wrongly convicted of murdering his father twenty years ago. Initially you are dismissive of the young man"s tale. You also get dna samples from two serial killers and the young man (because who doesn"t want to be genetically fingerprinted?). You have a family where one child has cystic fibrosis. Draw the results of an aso test for each individual in this family if ii-1 is afflicted, ii-2 is normal and ii-3 is a carrier. The gel below shows the rflp phenotypes of three individuals (ma, pa and uncle joe) at a tri-allelic locus.

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