BIOL 202 Study Guide - Coagulopathy, Haemophilia B, Genetic Counseling
Document Summary
The gene shows a classical sex- linked recessive inheritance. Half of michael and melanie"s children (2 boys) suffer from hemophilia b. However, neither the couple nor couple"s parents are affected. 1b) a phenotypically normal female is heterozygous for a rare autosomal recessive. Mendelian allele causing phenylketonuria, a disease caused by inability to convert amino acid phenylalanine to tyrosine. The same female is also heterozygous for a recessive x- linked allele causing red- green blindness. You are genetic counsellors and would like to help them understand their situation. Rosalind knows that her mother and maternal grandfather both developed the disorder. Rosalind also knows that the disorder is rare and has a simple (1 gene) basis. Below is the family tree of a group of individuals in the population. The nature of sex chromosomes was also known. F1 that is 50% symbol and 50% wild type (both sexes).