BIOCHEM 2EE3 Study Guide - Final Guide: Anesthetic, Batrachotoxin, Lidocaine

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Ions are very small but they cannot permeate through the membrane because still too large. Two basic types: ions channels and pumps (requires energy) Transmembrane proteins are required to help large molecules out but don"t require input of energy. Have hydrophobic and hydrophilic parts to the channel to that it ts well. They are smaller then the thickness of the membrane. Can diffuse through the membrane because they are hydrophobic. Especially when they bind to the ions they are transporting. There is no force required other then ion concentrations. Valinomycin - is a taxin which acts as a ion carrier. They kill other bacteria that does not have protective barrier. Has two gates, and glucose molecule is transported from the outside to the inside of the cell. Open - bottom part is where they are released. Has selectivity lter which is speci c to what they can carry.

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