BIOLOGY 2B03 Study Guide - Quiz Guide: Data Analysis, Chymotrypsin, Bzip2

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The structures of proteins and nucleic acid molecules can be determined by x-ray crystallography which identifies the locations of the atoms in the molecule by analyzing how x-rays are diffracted through a crystal. The data produced is a file of atomic coordinates which then gets deposited in the protein data bank as a . pdb file. The pdb is an open access database and can be accessed on line at http://www. rcsb. org. For this activity you will retrieve a file from the protein data. Bank and enter it into a program that can present the data as a 3 dimensional molecular model: go to http://www. rcsb. org to access the pdb. Biol: click on download file , select pdb file (text) , and download and save the file. The program is called pymol and takes the pdb file and converts it to a 3 dimension structure. The username is dec2010, and the password is mol2view.

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