HTHSCI 1H06 Study Guide - Spring 2018, Comprehensive Midterm Notes - Spinal Cord, Action Potential, Skeletal Muscle
12 Oct 2018
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Immunology: 3 stages = intrinsic, innate and adaptive. Intrinsic: already existing within body: mechanical sneezing, coughing, urination, skin, chemical low ph to kill bacteria, lysozyme, microbiological commensal flora, bacteria already on surface to block, physiological high temperature ie. fever. Innate: difference between immediate/resident and early induced? binding sites! Immediate (0-4 hours) = already residing in the cells ie. the macrophages, the complements vs. Adaptive: when apcs (antigen-presenting cells) interact with our t-cells. Apcs: antigen-presenting cells: tlr 3 recognize double stranded rna, like viruses. T-cells: 2 types: cd8 and cd4 interact with b-cells, t1 helper turns on macrophages, t1/2 helper turns on b-cells, divides rapidly + differentiates into effector t-cells. B-cells: from cd4 t-cells, activated, and then become plasma (shorter duration, they make antibodies) + memory (help with the secondary response being faster: rapidly divides (through help of t-cell growth factors) Cardiac development reason for development: a system is required to facilitate movement of materials.
