KINESIOL 2G03 Study Guide - Midterm Guide: Aldehyde Dehydrogenase, Acetaldehyde, Threshold Of Pain

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Loss of control in amount of use and frequency of use. Children of alcoholics are 4x more likely to become alcoholics. Monozygotic twins are more likely to both become alcoholics compared to dizygotic twins due to monozygotic twins sharing 100% of their genes. * dizygotic twins only share 50% of their genes. Those who are able to drink a lot and not feel drunk are considered low responders. Those who are high responders will drink alcohol and respond negatively feeling drunk and sick. Those who are low responders are more likely to become alcoholics. Males are more likely to developed alcoholism than women. Sons of alcoholics who also become alcoholics themselves are more likely to be low responders. Physiological mechanisms for why people are low and high responders: People can have two aldh2*1 genes low responder can have one aldh2*1 and one aldh2*2 mediocre responder can have two aldh2*2 high responder.

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