NURS 3102 Study Guide - Final Guide: Gas Gangrene, Reperfusion Injury, Metaplasia
20 Feb 2017
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Pre-readings(testable on quiz/final: copstead, l. , & banasik, j. (2010/2013). Chapter 4: cell injury, aging & death. Chapter 4 key points: reversible cell injury. Hydropic swelling is an early indicator of cell injury. Intracellular accumulations of abnormal endogenous or exogenous particles indicate a disorder of cellular metabolism. Damage from accumulation of abnormal intracellular protein is limited by chaperone proteins that attempt to refold the protein into its correct shape and by the ubiquitin-proteosome system that digests targeted proteins into fragments: cellular adaptation. Atrophy occurs when cells shrink and reduce their differentiated functions in response to a variety of normal and injurious factors. Hypertrophy an increase in cell mass accompanied by an augmented functional capacity. Hyperplasia an increase in number of cells. Metaplasia the replacement of one differentiated cell type w/ another. Dysplasia refers to the disorganized appearance of cells because of abnormal variations in size, shape, and arrangement.
