NSCI 323- Midterm Exam Guide - Comprehensive Notes for the exam ( 22 pages long!)

• School: Queen's University
• Department: Anatomy and Cell Biology
• Course: NSCI 323
• Professor: Pare

Document Summary

Ramon y cajal -> first person to understand and describe a neuron. Polarity axon has microtubules and filaments that are roads for things to go down retrograde v. anterograde microfilaments = little plastic proteins that make up neuron spines action occurs here. Primary active transport -> na/k/atpase pump sodium in, potassium out pump helps the neuron get its negative state back after action potential located in the nodes of ranvier. Chemical synapses travel in one direction only (pre and post synaptic) neurotransmitters are synthesized and packaged calcium comes in and vesicles fuse and release the neurotransmitter bind to receptors, ap happens, neurotransmitters undergo reuptake. Slow ion channels have cascades with g protein and camp. Electrical synapses don"t need neurotransmitters, travel in 2 directions (gap junctions + connexin) Neuronal integration spatial summation look at dendritic information coming in needs to cross threshold frequency temporal summation happen in a close sequence short decay time constant -> not activate threshold frequency.