KNPE 125 Study Guide - Midterm Guide: Acetyl-Coa, Myosin Head, Pyruvate Dehydrogenase
Document Summary
3 types of muscle: skeletal (voluntary, striated, smooth (involuntary, non-striated, cardiac (involuntary, striated) Connective tissue: epimysium (surrounds entire muscle, perimysium (divides muscle into sections called fascicles, endomysium (surrounds individual muscle fibres, tendon (attaches muscle to bone) Crossbridges: when myosin head binds to the actin active site a crossbridge is formed = contraction occurs, myosin undergoes a power stroke by pulling on actin and shortening the sarcomere. Length-tension relationship force of a muscle contraction reflects number of active cross- bridges. Fiber diameter larger fibers = greater forces, max. force linked to amount of muscle. Excitation-contraction coupling events that link an action potential to muscle contraction, controls how muscle contractions are turned on/off, involves release of calcium via the triad: t- Tubules (ap > muscle), sarcoplasmic reticulum (stores, releases, uptakes calcium), feet (include the dihydropyridine receptor which is voltage sensitive located in the membrane of t-tubule,