BLG 10A/B Final: BLG 10A – Chapter 16 Endocrine System

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Document Summary

Hormones: chemical messengers secreted by cells into extracellular space. Regulates: reproduction, growth, maintenance of electrolyte, water nutrients balance of the blood, regulation of cellular metabolism and energy balance, mobilization of body defenses. Amino acid based: most of hormones from single to peptide, to protein. Hormones influence cells that have receptors for them. (target cell) Water soluble: interact with receptors in the plasma membrane, then a. Fat soluble: act on receptors inside the ell, directly activates genes. The receptor and hormone make their way to the nuclear chromatin and on a specific gene to activate it. Blood levels of hormones reflect the balance between secretion and degradation/ excretion. The liver and kidneys are the major organs that degrade hormones, excreted in urine and feces. Hormone half-life and duration are limited and vary from hormone to hormone. Interaction with the cell another hormone being present. Permissiveness: one hormone cannot exert its full effect without.