BLG 143 Study Guide - Final Guide: Nuclear Pore, Nuclear Membrane, Nuclear Lamina

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7.3 Structure and Function at the Whole-Cell Level
Within a cell, the structure of each organelle and component correlates with its function. In
the same way, the overall size, shape and composition of a cell correlates with its function.
Cells are dynamic living things with interacting parts and constantly moving molecules.
The Dynamic Cell
Cells use and synthesize approximately 10 million ATP molecules/second.
Cellular membranes can catalyze more than 25k reactions/second.
Each membrane phospholipid can travel the breadth of its organelle or cell in under a
minute.
The hundreds of trillions of mitochondria inside you are replaced every 10 days, for as long
as you live.
The fluid plasma membrane’s composition is constantly changing.
Cell Systems I: Nuclear Transport
Nuclear envelope
Separates nucleus from rest of the cell
Nuclear lamina fibrous, supports structure, lattice-like sheet, provides attachment
points for each chromosome
2 membranes, each consisting of a lipid bilayer
Continuous with endoplasmic reticulum
Nuclear pores openings, functions as doors into and out of the nucleus, connect
nucleus with cytosol
Nuclear pore complex large protein complexes that cross the nuclear envelope
DNA doesn’t travel through nuclear pores, but the information coded in DNA is used to
synthesize RNA inside the nucleus.
Ribosomal RNAs rRNA, manufactured in the nucleolus where they bind to proteins to
form ribosomes, that’re then exported to the cytoplasm
Messenger RNAs mRNA, carry information required to manufacture proteins out to the
cytoplasm where protein synthesis takes place
How Molecules are Transported into the Nucleus
Viruses parasites that use the cell’s machinery to make copies of themselves
When a virus infects a cell, certain of its proteins enter the nucleus.
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Document Summary

7. 3 structure and function at the whole-cell level. Within a cell, the structure of each organelle and component correlates with its function. In the same way, the overall size, shape and composition of a cell correlates with its function. Cells are dynamic living things with interacting parts and constantly moving molecules. Cells use and synthesize approximately 10 million atp molecules/second. Cellular membranes can catalyze more than 25k reactions/second. Each membrane phospholipid can travel the breadth of its organelle or cell in under a minute. The hundreds of trillions of mitochondria inside you are replaced every 10 days, for as long as you live. The fluid plasma membrane"s composition is constantly changing. Ribosomal rnas rrna, manufactured in the nucleolus where they bind to proteins to. Dna doesn"t travel through nuclear pores, but the information coded in dna is used to form ribosomes, that"re then exported to the cytoplasm. Viruses parasites that use the cell"s machinery to make copies of themselves.

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