ENH 322 Final: Final exam review.docx

• School: Ryerson University
• Department: Environmental Health
• Course: ENH 322
• Professor: Lynette Ong

Document Summary

Inhaling airborne resp droplets from nose and throat of infected person. Spread by: resp droplets, direct contact w/discharges from nose/mouth of infected person. H. influenza part of normal flora in resp tract of healthy ppl. Pili or fimbrae: adherence to ciliated epithelial cells of upper resp tract. A-b toxin: similar to cholera; disrupts cell signaling by preventing host cell from switching off adenylate cyclase production. Adenylate cyclase: disrupts cell signaling and damages immune cells. Asymptomatic carriers have protective antibodies & no disease. Pili: initial attach to microvilli of nasopharyngeal epithelium. Tracheal cytotoxin: fragments of cell wall peptidoglycan; kills ciliated cells in trachea and leaves epithelium uncovered. Resp isolation of cases in separate hospital room & ppe. Minimize person to person contact by reducing overcrowding. Resp isolation of cases for 24h after treatment. Inhalation of tb bacilli aerosols direct contact/aerosols. <10 bacilli may initiate an infection occ. & social risk factors.