PAT 20A/B Study Guide - Midterm Guide: Epiphysis, Hyaline Cartilage, Synovial Joint
13 Jan 2017
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Document Summary
Breakdown of joint cartilage = loss of the joint space . In the knee-- the greatest loss of joint space often occurs in the medial femorotibial compartment: at nonpressure areas along the articular margin . Osseous metaplasia of synovial tissue leads to irregular outgrowth of new bone (osteophytes) Fragments of these osteophytes or of the articular cartilage itself may lead to intraarticular loose bodies ( joint mice: oa may also lead to changes in ligaments and muscles & nerves. Slowly destructive disorder of the articular cartilage: occurs from the inflammation caused when cartilage attempts to repair itself creating osteophytes or spurs. Progressive disruption of the smooth surface of the articular cartilage with development of surface cracks that deepen to involve the subchondral bone. Disease of the synovial joint where all tissues are affected: . Development of bone cysts: a fluid-filled hole that develops inside a bone. Formation of abnormal bony spurs at the joint margins.
