PSY 214 Quiz: Stimulants

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Document Summary

Cocaine exerts powerful effects on mood and behaviour. The cocaine high is characterized by feelings of ehileration and wellbeing. Smoked and iv induce a rush since the onset is so quick. At high doses or chronic use, it can give rise to irratibility anxiety, exhaustion, Physiologically, cocaine produces sympathomimetic effects (increased heart rate, vasoconstriction, hypertension, and hypothermia) high doses can be fatal due to sezures, heart failures, stroke, or hemorraghe. Most effects happen because of dat inhibition in nucleus accumbens and striatum. Early use of other substances indicate risk of future cocaine abuse. Neuroimagine shows that cocaine dependent subjects have abnormal prefrontal cortical functioning and cocaine related cues elicit da release in the dorsal striatum. Animal models : escalation of drug intake >> relapse to cocaine after period of abstinence?>> cocaine seeking behaviour despite aversive consequence>> increased motivation to take cocaine. Animal models: show that sensation seeking and impulsivity are traits that contribute to compulsive cocaine abuse.