MBB 222 Study Guide - Final Guide: Protoporphyrin Ix, Pyrrole, Reactive Oxygen Species

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Mbb222 exam vocab definitions: oxygen binding to globins. U9-01 must oxygen (o2) solubility and diffusion. Oxygen is poorly soluble in aqueous solutions meaning it cannot be carried to tissues sufficiently. U9-01 first o2 storage / transport protein. Transport proteins have developed so that oxygen can diffuse into them for effective transport and storage of oxygen. Oxygen can bind to a heme prosthetic group. Examples of proteins containing the heme group include: Iron is a transition metal that has a strong tendency to bind oxygen and is commonly incorporated for oxygen transport. Transition metals are suited for the reversible binding of oxygen molecules. Free iron promotes formation of highly reactive oxygen species that can damage dna and other macromolecules. Bound iron is used in cells to make it less reactive and therefore less harmful for organisms. A compound permanently associated with a protein that contributes to the. U9-01 first heme (= protoporphyrin + fe)