PHYSL212 Study Guide - Hypercapnia, Preganglionic Nerve Fibers, Carotid Body

• School: University of Alberta
• Department: Physiology
• Course: PHYSL212
• Professor: Saswati Das

Document Summary

Automatic rhythm created by the respiratory muscles. Neural network adjusts to accommodate changes in: metabolic demands (as reflected by changes in blood po2, pco2, and ph, varying mechanical conditions (e. g. changing posture, non-ventilatory behaviours (e. g. speaking, sniffing, eating) Inspiratory and expiratory groups and their motor output. Hypoxia (low po2), hypercapnia (high pco2 and low ph), and acidosis (low ph in blood) Send information to brainstem (to cranial nerves 9 (cb) and 10 (ab)) Contains: glomus cell (chemosensitive, sustentacular cells (provide support for cb) Glomus cells have a variety of voltage-gates ion channels. Primary feedback for assessing the effectiveness of ventilation and also the major source of tonic drive for breathing.