BIOL 1090 Study Guide - Final Guide: Ribose, Caat Box, Transfer Rna
Document Summary
There are two types of grooves of different width. Eukaryotic chromosomes are composed of proteins, dna and rna. Dna is wrapped around a nucleosome core of 8 histone proteins, and anchored by a 9th histone called histone h1 to form a complete nucleosome. Difference between nucleosome and complete nucleosome is presence of h1 histone, as well as, nucleosome core has 146 nucleotide pairs and complete nucleosome contains 166 pairs. An additional folding or supercoiling of the 11nm fiber to produce a 30nm fiber. 30nm fiber is the basic structural unit of the metaphase chromosome (dna in its most condensed form) Attachment of the 30nm fiber on many positions of a protein scaffold. Cohesin and condensin, in formation of mitotic chromosomes: Cohesin: ring shaped protein added to the 30nm dna fiber at interphase, cohesin functions to hold the sister chromatids together after dna synthesis.