PATH 3610 Study Guide - Final Guide: Mitral Valve Stenosis, Volume Overload, Nonsteroidal Anti-Inflammatory Drug

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Sclerosis: hardening (usually fibrous tissue, mostly formed from granulation tissue) Blood from heart large elastic a"s large muscular a"s small muscular a"s arterioles. Intima: inner lining of vessels, composed of endothelial cells and connective tissue. Vascular smooth muscle forms media (muscular layer) of muscular arteries. Nodes: pacemakers in heart coordinates contraction rate. Transmit signal to myocardium to control heart rate. Right side of heart pumps deoxygenated blood to lungs (slightly lower pressure system). Left side pumps oxygenated blood to rest of body. Redundant capacity: resting to highest (~70 200) Heart disease increases resting heart rate and lowers highest rate. Peripheral circulation svc and ivc r atrium r atrioventricular (tricuspid) valve. R ventricle pulmonary valve pulmonary arteries lung pulmonary vein . L atrium l atrioventricular (mitral) valve l ventricle aortic valve aorta peripheral circulation. Can stretch rapidly to deal with increased workload. Can undergo hypertrophy, but can"t regenerate or undergo hyperplasia. Hardening, thickening, and loss of elasticity of arteries.

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