PATH 3610 Final: Unit 3 Summary

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The term in ammation implies a complex, predetermined and nonspeci c response to injury, consisting of a microcirculatory response as well as mobilization of phagocytic cells; this is also termed the acute in ammatory response. It is characterized by the quartet of signs, redness, heat, swelling and pain, with loss of function also being considered a cardinal sign. However, if in ammation is prolonged, the term chronic in ammation is then used to describe a complex of tissue changes, consisting of a combined in ammatory and immune response against the foreign agent. Wherever in ammation occurs, it is described by adding the suf x itis . For example, in ammation of the appendix is termed. Appendicitis , in ammation of the colon is termed colitis , in ammation of the skin is termed dermatitis , in ammation of the stomach is termed gastritis , etc. Acute in ammation is essentially the rst line of defense against an injury.

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