POPM 3240 Study Guide - Quiz Guide: Net Present Value, Unimodality, Multimodal Distribution

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Must distinguish between those with disease and those without disease to understand the disease and provide proper care. Tests must be able to accurately do this! Test: any critical examination, observation, or evaluation used to determine health and disease outcomes and potential exposures. Screening test: population approach on apparently healthy people to detect subclinical disease, provides early indication. Diagnostic test: used on sick people to confirm, classify, inform treatment, or provide prognosis for a particular disease. Bimodal distribution: has 2 peaks, allows clear separation of population (those with and those without disease) Unimodal distribution: most common, has 1 peak, must choose cutoff to separate people (not always easy!) Both distri(cid:271)utio(cid:374)s ha(cid:448)e a (cid:862)gray zo(cid:374)e(cid:863) i(cid:374) (cid:449)hi(cid:272)h people (cid:272)ould (cid:271)elo(cid:374)g to either group. Both allo(cid:449) (cid:272)lear separatio(cid:374) fro(cid:373) o(cid:448)erall (cid:862)(cid:374)or(cid:373)al(cid:863) fro(cid:373) (cid:862)a(cid:271)(cid:374)or(cid:373)al(cid:863) Validity: test"s a(cid:271)ility to disti(cid:374)guish those (cid:449)ho ha(cid:448)e disease fro(cid:373) those (cid:449)ho do(cid:374)"t. Sensitivity: ability of test to correctly identify those who have the disease.