ZOO 3210 Study Guide - Final Guide: Proximal Tubule, Collecting Duct System, Reabsorption

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Capsular fluid becomes the primary urine: barrier b/w the blood and capsular fluid is very porous lots of fenestrae. Allows for small molecules to pass through, but not proteins. Not metabolized once you introduce it into the body, it can"t be digested or converted into other things (inert: clearance of inulin can be used to measure gfr. Ideal molecule to be measured because it can be filtered by kidney, but can"t be secreted/reabsorbed/etc. Inject a known amount measure [ ] in blood measure amount in urine measure urine flow, then you can calculate gfr: gfr = (uin x v)/pin. Uses na+ movement to power glucose movement into cell: glucose then exits the cell via channels, na+ gradient must be maintained using an na+/k+ 75% of filtrate is absorbed back into blood: filtrate is the same osmolarity as blood at the end of (300mosm, note that there is a limit to how much can be reabsorbed.

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