BIOL373 Study Guide - Midterm Guide: Macula Densa, Afferent Arterioles, Renal Corpuscle

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Role of the kidney regulation of extracellular fluid volume and blood pressure. Integrates kidney function with behaviour ie: drinking water. Regulates ion balance: na+ (and thus ecf volume and osmolarity, k+, ca2+ Regulates plasma ph acid base relationships: acidic removes h+, conserve bicaronate, basic opposite. Breakdown products of hormones, hemoglobin: exogenous. Renin part of endocrine cascade regulating na+ Produces enzyme that participates in ca2+ homeostasis. Proximal tubule descending limb loop of henle ascending limb distal tubule collecting duct bladder. Renal circulation afferent arteriole glomerulus efferent arterioles peritubular capillaries venule. Juxtamedullary nephron circulation afferent arteriole glomerulus efferent arterioles peritubuluar capillaries / vasa recta venules. Kidneys process 180l plasma/day urinate 1. 5l therefore 99% is reabsorbled. Filtration movement of water/solutes into tubules: only occurs in renal corpuscles, once in tubules, filtrate will be excreted or reabsorbed. Reabsorption: movement of water/solutes from filtrate back into blood (peritubular capillaries. Secretion: removing molecules from blood, adding them to filtrate, more selective than filtration.

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