FNH 250 Study Guide - Final Guide: Megaloblastic Anemia, Superoxide Dismutase, Selenium Deficiency
31 Jan 2019
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Burning feet syndrome: pantothenic acid deficiency, gi neuro disturbances. Crypt glands: between villi, secrete intestinal juices into si. Microcytic anemia: vit b6 deficiency, heme synth impaired-> small rbc w/o heme. Megaloblastic anemia: folate deficiency, fewer circulating rbcs, but each one larger/immature. Dietary folate equivalent (dfe): folate intake calculated as. Pernicious anemia: vit b12 deficiency from body"s inability to absorb vit b12: vit b12 deficiency exhibit megaloblastic anemia. Cretinism: fe deficiency curing pregnancy-> irreversible mental and physical retardation in offspring. Goiter: large lump in neck from enlarged thyroid gland from iodine deficiency. Retinoids: carotenoids that can be converted to vit a: beta-carotene, alpha-carotene, beta- cryptoxanthin: cannot be converted to vit a: lycopene, lutein, zeaxanthin. Hemolytic anemia: deficiency of vit e, bursting of rbc from oxidative damage to membranes. Mnsod: manganese superoxide dismutase, cofactor is mn, neutralize superoxide (o2-) thats highly reactive and used by immune sys to kill pathogens: cusod/znsod2. Catalase: enzyme needed to neutralize h2o2, needs fe to function.
