MICB 202 Study Guide - Mhc Class I, Mhc Class Ii, Adaptive Immune System
Document Summary
Immunology review questions topics 1 and 2. Prrs are receptors on cells of the innate immune responses (or the intracellular vesicles) that recognized pathogen associated molecular patterns these are molecules that are found on the surfaces of pathogens. These molecular patterns are essential to the pathogen and therefore, do not undergo frequent mutation. Prrs may also be found as secreted proteins in the blood/lymph fluids and mucous secretions. Some cell surface prrs are involved in the binding and phagocytosis of a pathogen by a phagocytic cell. Other cell surface or intracellular prrs activate signaling pathways upon binding, and result in transcription of cytokine genes. The newborn mouse would lack mature t cells and thus be unable to initiate either cell mediated or humoral responses against a pathogen. This is because the thymus in a newborn is vital for the proper maturation of t cells.
