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Learning Objectives for Homeostasis Part 2.docx

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Anatomy and Physiology
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Learning Objectives for Homeostasis Part 23Objective describe the functional organization of the hypothalamic pituitary axis pp 601 608 The sensor y input information goes to the CNS neuroendocrine origins of signals which leads to the hypothalamus Hypothalamus releases hypothalamic hormones releasing factors to the anterior pituitary as first target or to posterior pituitaryThe post pituitary produces oxytocin which targets smooth muscle and mammary glands it also produces vasopressin which targets arterioles The ant pituitary makesaCorticotropin ACTH targets the adrenal cortex which then produces cortisol corticosterone and aldosterone These target many tissuesbThyrotropin targets the thyroid which produces thyroxine t4 and triiodithyroxine t3 These target the muscles and livercFSH follicle stimulating hormone targets the ovaries which produces progesterone and estradiol which targets the reproductive organsdLuteinizing hormone LH targets the testes which produce testosterone which targets the reproductive organseSomatotropin GH targets liver and bonefProlactin targets mammary glands4The hypothalamus is a collecting centre for info regarding the internal wellbeing of the body It receives information from different sources pain change in temperature depressingexciting thoughts olfactory stimuli conc of nutrientselectrolyeswater in body5Hypothalamus is neural therefore it produces a number of releasing factors RF also called releasing hormones RH which travel to anterior pituitary via the HYPOTHALAMICHYPOPHYSEAL PORTAL SYSTEM blood vessels Hypothalamus also produces oxytocin and vasopressin ADH released to the posterior pituitary whre they are stored The releasing factors RF include GHRH TRH GnRH LH FSH CRH which are stimulating factors and somatostatin dopamine which are inhibiting factors IF6Almost all secretion by the pituitary is controlled by the HYPOTHALAMUSaAnterior pituitary is controlled by the hypothalamic releasing or inhibiting hormones factorsbPosterior pituitary receives hormones from the hypothalamus7The hypothalamicpituitaryendocrine organ axis is that hormones stimulate other endocrine organs to release their hormones
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