ANP1105- Midterm Exam Guide - Comprehensive Notes for the exam ( 76 pages long!)

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1105
• Professor: Joanne Savory

Document Summary

11. 4 the resting membrane potential depends on differences in ion concentration and permeability. The measure of the potential energy of separated electrical charges is called voltage (v) or potential. Current (i) is the flow of electrical charge from one point to another. Oh(cid:373)"s la(cid:449) gi(cid:448)es the relatio(cid:374)ship a(cid:373)o(cid:374)g these: i = v/r. In the body, ions provide the electrical charges; cellular plasma membranes provide resistance to ion flow. The membranes contain leakage channels (nongated, always open) and gated channels. A resti(cid:374)g (cid:374)euro(cid:374) e(cid:454)hi(cid:271)its a resti(cid:374)g (cid:373)e(cid:373)(cid:271)ra(cid:374)e pote(cid:374)tial, (cid:449)hi(cid:272)h is 70 (cid:373)v (cid:894)i(cid:374)side (cid:374)egati(cid:448)e(cid:895). It is due both to differences in sodium and potassium ion concentrations inside and outside the cell and to differences in permeability of the membrane to these ions. The ionic concentration differences result from the operation of the sodium-potassium pump, which ejects 3 na+ from the cell for each 2 k+ transported in.