ANP 1107 Final: ANP1107 Exam notes part 1
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Region proportion of total renal blood flow % Rate of appearance in the urine = the rate of appearance in the ltrate. Amount excreted in the urine per unit of time = amount ltered by the glomerulus per unit of time. Urine ow rate x urine concentration = rate at which plasma is ltered x. It requires a continuous intravenous infusion to maintain a constant plasma level since inulin is not endogenous. Its clearance gives an accurate estimate of gfr. However, creatinine which is produced by muscle is present in plasma, creatinine is freely ltere. Therefore, in many clinical settings creatinine is used to estimate or measure gfr. Creatinine can be used to measure gfr in man and it is routinely performed in suspected cases of renal disease by the nephrologists. Clearance is a volume of plasma from which all the substance has been completely removed and excreted into the urine.