ANP 1107 Study Guide - Final Guide: Spermiogenesis, Efferent Ducts, Spermatogonium

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Leydig cells: interstitial, make androgens, react to lh. Testicular veins: form pampiniform plexus cools down blood. Acessory glands: seminal vesicles- make 70% semen volume, yellow, fructose, prostate gland: milky secretion, 1/3 semen volume, enzymes, bulbourethral glands: inferior to prostate, clear mucus to spongy urethra, alkaline. = sertoli cells + spermatogenesis intermediates, 80% of testicular mass. Leydig cells: make testosterone, vascularized, receptors for lh, testosterone support spermatogenesis. Sertoli cells: sit on basement membrane, adluminal and basal compartments, stimulated by fsh to support spermatogenesis, secrete abp and inhibin. Gonadotropins: target testis, glycoproteins, water soluble (bind to surface receptor) Fsh: stimulates spermatogeneisis, stim sertoli cells to release abp, basically enhances testosterone"s effects. Lh: stimulates leydig cells to secrete testosterone, testosterone inhibits gnrh. Gnrh: secreted by hypothalamic neurons, stimulates fsh and lh secretion by ant pituitary. Inhibin: released by sertoli cells, inhibits fsh only. Primary spermatocyte: made by mitosis, where meiosis starts, first round 2 secondary spermatocytes.

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