BCH 3120 Study Guide - Quiz Guide: Thickening Agent, Guar Gum, Colloidal Gold

• School: University of Ottawa
• Department: Biochemistry
• Course: BCH 3120
• Professor: Elaine Beaulieu

Document Summary

Microcapsule wall material, suspending agent, binder, coating mater4ial. Hydroxypropyl cellulse viscosity-imparting agent, microcapsule wall material, granulating agent. Emulsi er, viscosity-imparting agent, gelling agent, suspending agent, binder, disintegrate. Lubricant for capsules and tablets, viscosity-imparting agent, adsorbent. Diagnostic and therapeutic agents in nuclear medicine i. e. colloidal gold au 198; technetium 99m, sulfur colloid: cross-linked polymers. Particularly useful for sensitive therapeutics (i. e. biopharmaceutical products dna, proteins); also used for synthetic drugs. Oil soluble drug incorporates in lipid bilayer, water soluble into the entrapped aqueous phase. Additional advantage arises from ability to target tumors (enhanced permeability and retention) Therapeutic agents either adsorbed onto surface, dissolved or dispersed throughout or entrapped by nanoparticle. 2-100nm: nanocrystrals as imaging agents: drug-polymer conjugates. Covalent bonding between drug and polymer used to produce water soluble conjugates. 0. 2-5 m: microparticles: micelles used to solubilize poorly water-soluble drugs; requires surfactant concentration > critical micelle concentration (cmc) 3-80nm: natural and synthetic surfactant micelles: microemulsions.