BIO 1140 Final: Revision 10

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**tubulin is involved as the mitoic spindles in mitosis (microtubules) Describe and compare the role of the diferent phases of the cell cycle, including the various molecular checkpoints. Explain how the cell cycle is regulated (internal and external signals) Understand and discuss the relaionship between the cell cycle"s regulaion and the cell"s mechanisms for survival vs death. Interphase (g1 > s > g2) prophase prometaphase metaphase anaphase telophase + cytokinesis. A: metaphase (at prophase, its only separaing & dissolving the nuclear membrane, also extending the spindles, not yet forming with the chromosomes) Some cells divide very oten (roots [plants], epithelium [skin, intesines], etc ) Some do not divide in adults (rbcs, muscles, most neurons) During the 70s, the big quesion was how does the cell know what to do and when to do it?". Cancer, apoptosis, mutaions, many consequences and failsafe mechanisms. **interphase takes up most of the ime in mitosis.

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