BPS 1101 : TOPIC 8- TOBACCO.docx

• School: University of Ottawa
• Department: Biopharmaceutical sciences
• Course: BPS 1101
• Professor: Mary Theresa Howard

Document Summary

Today 10k cigarettes per year and inhale deeply and we hold smoke in lungs messages from being propagated: avg smoker smokes 10k of cigarettes a year, nicotine acts as the addictive substance and you only need 2mg per cigarette to addict a smoker, nicotine acts on acetylcholine receptors, nicotine is an agonist at low doses agonists send messages without the normal messsenger, nicotine is an antagonist at high doses, causing second messenger to be inhibited and block normal nerves or, deep drag for relaxation = antagonist = high dose of nicotine, nicotine stimulate dopamine release from the dopamine system, nicotine stimulates the heart muscles and increases the heart rate and could lead to heart attacks carbon monoxide for heart attacks. Lethal dose of nicotine is 60mg: benzopyrenes carcinogenic by damaging dna and causing mutations, nitrosamines, aldehydes, epoxides, aza arenes, trace metals.