ANTB15H3 Study Guide - Final Guide: Melanin, Ultraviolet, Melanocyte
Document Summary
Lecture: skin color is an interactions of cell function, bio-chemistry and geography, skin function: Protection against ultraviolet ray (uv: layers of skin. Keratinocytes (basal cells) it is the predominant cell of epidermis, the important for skin pigmentation formation of barrier that fight against the environment pathogens. Contain collagens fibbers (strength), nerves, swear glands, hair follicles, and blood vessels. Produced by melanocytes, located at the lowest level of epidermis. Melanin are contained in melanosomes (an organelle of melanocytes), and they move to the upper layer of epidermis. (*melanin molenosome molanocytes) Skin color is depend on how much melanin is distributed and rate of melanin synthesis (how active the melanocytes are) # of melanocytes are same across population. Melanin are regulated by mc1r (receptors) that leads the production of the black and brown pigments eumelanin. Eumelanin one of the melanin type produce brown/black produce when tyrosinase is presented (the more eumelanine, the darker skins you will have)
