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BIOC33H3 Study Guide - Quiz Guide: Achlorhydria, Central Nervous System, Argon Plasma Coagulation

Biological Sciences
Course Code
Stephen Reid
Study Guide

of 5
Chapter 42: Upper Gastrointestinal Problems
Nausea and vomiting are found in a wide variety of gastrointestinal (GI) disorders.
They are also found in conditions that are unrelated to GI disease, including pregnancy,
infectious diseases, central nervous system (CNS) disorders (e.g., meningitis),
cardiovascular problems (e.g., myocardial infarction), metabolic disorders (e.g., diabetes
mellitus), side effects of drugs (e.g., chemotherapy, opioids), and psychologic factors
(e.g., fear).
Vomiting can occur when the GI tract becomes overly irritated, excited, or distended.
o It can be a protective mechanism to rid the body of spoiled or irritating foods and
o Pulmonary aspiration is a concern when vomiting occurs in the patient who is
elderly, is unconscious, or has other conditions that impair the gag reflex.
o The color of the emesis aids in identifying the presence and source of bleeding.
Drugs that control nausea and vomiting include anticholinergics (e.g., scopolamine),
antihistamines (e.g., promethazine [Phenergan]), phenothiazines (e.g., chlorpromazine
[Thorazine], prochlorperazine [Compazine]), and butyrophenones (e.g., droperidol
The patient with severe or prolonged vomiting is at risk for dehydration and acid-base and
electrolyte imbalances. The patient may require intravenous (IV) fluid therapy with electrolyte
and glucose replacement until able to tolerate oral intake.
Upper Gastrointestinal Bleeding
The mortality rate for upper GI bleeding remains at 6% to 10% despite advances in intensive
care, hemodynamic monitoring, and endoscopy.
The severity of bleeding depends on whether the origin is venous, capillary, or arterial.
Bleeding ulcers account for 50% of the cases of upper GI bleeding.
Drugs such as aspirin, nonsteroidal antiinflammatory agents, and corticosteroids are a major
cause of upper GI bleeding.
Although approximately 80% to 85% of patients who have massive hemorrhage spontaneously
stop bleeding, the cause must be identified and treatment initiated immediately.
The immediate physical examination includes a systemic evaluation of the patient’s condition
with emphasis on blood pressure, rate and character of pulse, peripheral perfusion with
capillary refill, and observation for the presence or absence of neck vein distention. Vital signs
are monitored every 15 to 30 minutes.
The goal of endoscopic hemostasis is to coagulate or thrombose the bleeding artery. Several
techniques are used including thermal (heat) probe, multipolar and bipolar electrocoagulation
probe, argon plasma coagulation, and neodymium:yttrium-aluminum-garnet (Nd:YAG) laser.
The patient undergoing vasopressin therapy is closely monitored for its myocardial, visceral, and
peripheral ischemic side effects.
The nursing assessment for the patient with upper GI bleeding includes the patient’s level of
consciousness, vital signs, appearance of neck veins, skin color, and capillary refill. The abdomen
is checked for distention, guarding, and peristalsis.
The patient who requires regular administration of ulcerogenic drugs, such as aspirin,
corticosteroids, or NSAIDs, needs instruction regarding the potential adverse effects
related to GI bleeding.
During the acute bleeding phase an accurate intake and output record is essential so that
the patient’s hydration status can be assessed.
Once fluid replacement has been initiated, the older adult or the patient with a history of
cardiovascular problems is observed closely for signs of fluid overload.
The majority of upper GI bleeding episodes cease spontaneously, even without intervention.
Monitoring the patient’s laboratory studies enables the nurse to estimate the effectiveness of
The patient and family are taught how to avoid future bleeding episodes. Ulcer disease, drug or
alcohol abuse, and liver and respiratory diseases can all result in upper GI bleeding.
Oral Infections and Inflammations
May be specific mouth diseases, or they may occur in the presence of systemic disorders such as
leukemia or vitamin deficiency.
The patient who is immunosuppressed (e.g., patient with acquired immunodeficiency syndrome
or receiving chemotherapy) is most susceptible to oral infections. The patient on oral
corticosteroid inhaler treatment for asthma is also at risk.
Management of oral infections and inflammation is focused on identification of the cause,
elimination of infection, provision of comfort measures, and maintenance of nutritional intake.
Oral (or Oropharyngeal) Cancer
May occur on the lips or anywhere within the mouth (e.g., tongue, floor of the mouth, buccal
mucosa, hard palate, soft palate, pharyngeal walls, tonsils).
Head and neck squamous cell carcinoma is an umbrella term for cancers of the oral cavity,
pharynx, and larynx. Accounts for 90% of malignant oral tumors.
The overall goals are that the patient with carcinoma of the oral cavity will (1) have a
patent airway, (2) be able to communicate, (3) have adequate nutritional intake to
promote wound healing, and (4) have relief of pain and discomfort.
There is no one single cause of gastroesophageal reflux disease (GERD). It can occur
when there is reflux of acidic gastric contents into the esophagus.
Predisposing conditions include hiatal hernia, incompetent lower esophageal sphincter,
decreased esophageal clearance (ability to clear liquids or food from the esophagus into
the stomach) resulting from impaired esophageal motility, and decreased gastric
A complication of GERD is Barrett’s esophagus (esophageal metaplasia), which is
considered a precancerous lesion that increases the patient’s risk for esophageal cancer.
Most patients with GERD can be successfully managed by lifestyle modifications and
drug therapy.
Drug therapy for GERD is focused on improving LES function, increasing esophageal
clearance, decreasing volume and acidity of reflux, and protecting the esophageal
Because of the link between GERD and Barrett’s esophagus, patients are instructed to see
their health care provider if symptoms persist.
The two most common types of hiatal hernia are sliding and paraesophageal (rolling).