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Department
Biological Sciences
Course Code
BIOC34H3
Professor
Stephen Reid

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Lecture 16 Study Notes
Hydrostatic pressure P = Pcapillaries Pisf
oISF = interstitial fluid
oPcap = hydrostatic pressure in capillaries
Hydrostatic pressure in capillaries drives fluid out of the capillary
(i.e. filtration) and is highest on arterial side, lower on the venous side
Causes fluid movement down pressure gradient
oPisf = hydrostatic pressure in the interstitial fluid
Oncotic pressure = cap isf
oOncotic Pressure (opposes hydrostatic pressure) is exerted by proteins and
drives fluid into capillaries
cap = oncotic pressure in the capillaries
This pressure is constant throughout the capillary beds
Lots of protein in plasma flowing in capillary bed hence oncotic
pressure
isf = oncotic pressure in the interstitial fluid
This pressure is generally 0 in the isf because the isf has
virtually no proteins
Net Filtration Pressure = P -
oOr NFP = Hydrostatic Pressure (fluid out c) Osmotic Pressure
(fluid in c)
oIf NFP is positive, then filtration of fluid occurs (flowing out of capillaries)
oBut if NFP is negative, then absorption occurs (flowing into capillaries)
oNote:
On the arterial side of capillary bed, NFP is positive, so fluid is drawn
out of capillaries (filtration outward)
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Description
Lecture 16 Study Notes Hydrostatic pressure P = Pcapillaries Pisf o ISF = interstitial fluid o Pcap = hydrostatic pressure in capillaries Hydrostatic pressure in capillaries drives fluid out of the capillary (i.e. filtration) and is highest on arterial side, lower on the venous side Causes fluid movement down pressure gradient o Pisf = hydrostatic pressure in the interstitial fluid Oncotic pressure = cap isf o Oncotic Pressure (opposes hydrostatic pressure) is exerted by proteins and drives fluid into capillaries cap = oncotic pressure in the capillaries This pressure is constant throughout the capillary beds Lots of protein in plasma flowing in capillary bed hence oncotic pressure isf = oncotic pressure in the interstitial fluid This pressure is generally 0 in the isf because the has virtually no proteins Net Filtration Pressure = P - o Or NFP = Hydrostatic Pressure (fluid out c) Osmotic Pressure (fluid in c) o If NFP is positive, theniltration of fluid occurs (flowing out of capillaries) o But if NFP is negative, thenabsorption occurs (flowing into capillaries) o Note: On the arterial side of capillary bed, NFP is positive, so fluid is drawn out of capillaries (filtration outward) www.notesolution.com
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