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University of Toronto Scarborough
Biological Sciences
Stephen Reid

1Lecture 10 Lung Mechanics continued and Spirometry1 The Ideal Gas LawThe Ideal Gas Law is as followsPVnRTWhere P is gas pressure V is the volume in which the gas is contained n is the number of moles of gas R is the universal gas constant and T is temperature in degrees Kelvin Pressure can be calculated by the equation PnRTV Boyles Law which states that for a given quantity of gas in a chamber the gas pressure is inversely proportional to the volume of the chamber There are three main pressures associated with pulmonary mechanics as well as two important pressure differentials Atmospheric pressure interalveolar pressure and interpleural pressure are the three pressure values and the important pressure differentials are between the former two which is the driving force for moving air in and out of the lungs and between the latter two called transpulmonary pressure which is the driving force for lung expansion Air flow in and out of the lungs is caused by differences between atmospheric pressure and pressure inside the lungs interalveolar pressure If the former pressure is higher than the latter air will flow into the lungs and vice versa We can calculate air flow via this equationAir Flowatmospheric pressureinteralveolar pressureR
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